Friday, April 28, 2006

Undergrad B school rankings

Businessweek just cooked out a ranking list of Best undergrad B-schools. Interestingly, I found no Harvard, Yale, Columbia, Brown, or Dartmouth in the list. My guess would be that those Ivy League schools do not have a so-called B-school for undergrads, rather just a major. At Michigan, select sophomores could grasp a BBA degree beared big M through 2 year study at Ross B School.

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Tuesday, April 25, 2006

Mod Path May 06

Content

FREE special online issue on Dermatopathology

Correlation of cytologic findings and chromosomal instability detected by fluorescence in situ hybridization in breast fine-needle aspiration specimens from women at high risk for breast cancer Nour Sneige, Baoshun Liu, Guosheng Yin, Yun Gong & Banu K ArunMod Pathol 2006; 19 5: 622-629

Prostate cancer detected by uPM3: radical prostatectomy findings David G Bostwick, Victor E Gould, Junqi Qian, Martin Susani & Michael MarbergerMod Pathol 2006; 19 5: 630-633

Identification of SYT-SSX transcripts from synovial sarcomas using RT-multiplex PCR and capillary electrophoresis John A Thorson, Helmut C Weigelin, Robert E Ruiz, Jennifer K Howard & David R LucasMod Pathol 2006; 19 5: 641-647

Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse Fahd Al-Mulla, Abdulla I Behbehani, Milad S Bitar, Govindarajulu Varadharaj & James J Going Mod Pathol 2006; 19 5: 648-658

Variability in the expression of polycomb proteins in different normal and tumoral tissues. A pilot study using tissue microarrays Margarita Sánchez-Beato, Esther Sánchez, Joaquín González-Carreró, Manuel Morente, Ana Díez, Lydia Sánchez-Verde, María Carmen Martín, Juan C Cigudosa, Miguel Vidal & Miguel A Piris Mod Pathol 2006; 19 5: 684-694

CXCR4 and VEGF expression in the primary site and the metastatic site of human osteosarcoma: analysis within a group of patients, all of whom developed lung metastasis Yoshinao Oda, Hidetaka Yamamoto, Sadafumi Tamiya, Shuichi Matsuda, Kazuhiro Tanaka, Ryohei Yokoyama, Yukihide Iwamoto & Masazumi TsuneyoshiMod Pathol 2006; 19 5: 738-745

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Monday, April 24, 2006

FDA's updated contact lens advice

  • Stop using Bausch and Lomb ReNu with MoistureLoc products and discard all remaining MoistureLoc solution including partially used or opened bottles.
  • Consult your eye care professional concerning use of an appropriate alternative cleaning/disinfecting product.
  • Consider performing a "rub and rinse" lens cleaning method, rather than a no rub method, regardless of which cleaning/disinfecting solution used, in order to minimize the number of germs and reduce the chances of infection.

  • Continue to follow proper lens care practices:
  • Wash hands with soap and water, and dry (lint-free method) before handling lenses.
  • Wear and replace lenses according to the schedule prescribed by the doctor.
  • Follow the specific lens cleaning and storage guidelines from the doctor and the solution manufacturer.
  • Keep the contact lens case clean and replace every 3-6 months.
    Remove the lenses and consult your doctor immediately if you experience symptoms such as redness, pain, tearing, increased light sensitivity, blurry vision, discharge, or swelling.

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Friday, April 21, 2006

JNCI apr 2006

JNCI Apr 2006

Antitumor Activity of ZSTK474, a New Phosphatidylinositol 3-Kinase Inhibitor J Natl Cancer Inst 2006; 98: 545-556

Assessing Prostate Cancer Risk: Results from the Prostate Cancer Prevention Trial J Natl Cancer Inst 2006; 98: 529-534
Variables that predicted prostate cancer included higher PSA level, positive family history of prostate cancer, and abnormal DRE result, whereas a previous negative prostate biopsy was associated with reduced risk. Neither age at biopsy nor PSA velocity contributed independent prognostic information. Higher PSA level, abnormal DRE result, older age at biopsy, and African American race were predictive for high-grade disease (Gleason score 7) whereas a previous negative prostate biopsy reduced this risk.


Evaluation of Prostate-Specific Antigen Declines for Surrogacy in Patients Treated on SWOG 99-16 J Natl Cancer Inst 2006; 98: 516-521.


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Thursday, April 20, 2006

AJSP Apr 2006

AJSP Apr 2006

Recommendations for the Supervision of Pathology Assistants. Association of Directors of Anatomic and Surgical Pathology 537

Mammary NOS-Type Sarcoma With CD10 Expression: A Rare Entity With Features of Myoepithelial Differentiation. Leibl, Sebastian MD; Moinfar, Farid MD 450

Gastrointestinal Stromal Tumors of the Jejunum and Ileum: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 906 Cases Before Imatinib With Long-term Follow-up. Markku Miettinen, MD; Hala Makhlouf, MD; Leslie H. Sobin, MD; Jerzy Lasota, MD 477

Glycogenic Hepatopathy: An Underrecognized Hepatic Complication of Diabetes Mellitus. Michael Torbenson, MD; Yunn-Yi Chen, MD, PhD; Elizabeth Brunt, MD; Oscar W. Cummings, MD; Marcia Gottfried, MD; Shriram Jakate, MD, FRCPath; Yao-Chang Liu, MD; Matthew M. Yeh, MD, PhD; Linda Ferrell, MD 508

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Monday, April 17, 2006

Cancer Research apr 2006

Vol 66, issue 8 , Apr 2006

Meeting Report: Antiangiogenesis and Drug Delivery to Tumors: Bench to Bedside and Back Dan G. Duda Cancer Res 2006 66: 3967-3970

KRAS Mutation Status Is Predictive of Response to Cetuximab Therapy in Colorectal Cancer Astrid Lièvre, Jean-Baptiste Bachet, Delphine Le Corre, Valérie Boige, Bruno Landi, Jean-François Emile, Jean-François Côté, Gorana Tomasic, Christophe Penna, Michel Ducreux, Philippe Rougier, Frédérique Penault-Llorca, and Pierre Laurent-Puig Cancer Res 2006 66: 3992-3995

Id1 Transcription Inhibitor–Matrix Metalloproteinase 9 Axis Enhances Invasiveness of the Breakpoint Cluster Region/Abelson Tyrosine Kinase–Transformed Leukemia CellsMargaret Nieborowska-Skorska, Grazyna Hoser, Lori Rink, Maciej Malecki, Plamen Kossev, Mariusz A. Wasik, and Tomasz Skorski Cancer Res 2006 66: 4108-4116

Multiple Adaptive Mechanisms to Chronic Liver Disease Revealed at Early Stages of Liver Carcinogenesis in the Mdr2-Knockout Mice Mark Katzenellenbogen, Orit Pappo, Hila Barash, Naama Klopstock, Lina Mizrahi, Devorah Olam, Jasmine Jacob-Hirsch, Ninette Amariglio, Gidi Rechavi, Leslie Ann Mitchell, Ron Kohen, Eytan Domany, Eithan Galun, and Daniel Goldenberg Cancer Res 2006 66: 4001-4010

Two-Dimensional Transcriptome Profiling: Identification of Messenger RNA Isoform Signatures in Prostate Cancer from Archived Paraffin-Embedded Cancer Specimens Hai-Ri Li, Jessica Wang-Rodriguez, T. Murlidharan Nair, Joanne M. Yeakley, Young-Soo Kwon, Marina Bibikova, Christina Zheng, Lixin Zhou, Kui Zhang, Tracy Downs, Xiang-Dong Fu, and Jian-Bing Fan Cancer Res 2006 66: 4079-4088.

Targeting Oncogenes to Improve Breast Cancer Chemotherapy Laura A. Christensen, Rick A. Finch, Adam J. Booker, and Karen M. Vasquez Cancer Res 2006 66: 4089-4094.

The Kinase Mirk/Dyrk1B Mediates Cell Survival in Pancreatic Ductal Adenocarcinoma Xiaobing Deng, Daina Z. Ewton, Sheena Li, Asghar Naqvi, Stephen E. Mercer, Steve Landas, and Eileen Friedman Cancer Res 2006 66: 4149-4158.

Development of Real-time Subcellular Dynamic Multicolor Imaging of Cancer-Cell Trafficking in Live Mice with a Variable-Magnification Whole-Mouse Imaging System Kensuke Yamauchi, Meng Yang, Ping Jiang, Mingxu Xu, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, Abdool R. Moossa, Michael Bouvet, and Robert M. Hoffman Cancer Res 2006 66: 4208-4214.

Tumor Imaging Using a Picomolar Affinity HER2 Binding Affibody Molecule Anna Orlova, Mikaela Magnusson, Tove L.J. Eriksson, Martin Nilsson, Barbro Larsson, Ingmarie Höidén-Guthenberg, Charles Widström, Jörgen Carlsson, Vladimir Tolmachev, Stefan Ståhl, and Fredrik Y. Nilsson Cancer Res 2006 66: 4339-4348.

Characterization of a Novel Human Tumor Antigen Interleukin-13 Receptor 2 Chain Koji Kawakami, Masaki Terabe, Mariko Kawakami, Jay A. Berzofsky, and Raj K. Puri Cancer Res 2006 66: 4434-4442.

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Int J Cancer 119:1

International Journal of Cancer
Volume 119, Issue 1, 2006.

MMP-2 mediates ethanol-induced invasion of mammary epithelial cells
over-expressing ErbB2.
Zunji Ke, Hong Lin, Zhiqin Fan, Tian-Quan Cai, Rebecca A. Kaplan, Cuiling Ma, Kimberly A. Bower, Xianglin Shi, Jia Luo. Pages: 8-16

Statins revert doxorubicin resistance via nitric oxide in malignant
mesothelioma.
Chiara Riganti, Sara Orecchia, Gianpiero Pescarmona, Pier Giacomo Betta, Dario Ghigo, Amalia Bosia. Pages: 17-27

Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene. Masami Suganuma, Miki Kurusu, Kaori Suzuki, Emi Tasaki, Hirota Fujiki. Pages: 33-40

Reclassification of oligoastrocytomas by loss of heterozygosity studies Marica Eoli, Lorena Bissola, Maria Grazia Bruzzone, Bianca Pollo, Carmelo Maccagnano, Tiziana De Simone, Lorella Valletta, Antonio Silvani, D Bianchessi, Giovanni Broggi, Amerigo Boiardi, Gaetano Finocchiaro. Pages: 84-90

Serological immune response to cancer testis antigens in patients with pancreatic cancer Andreas Wadle, Boris Kubuschok, Jochen Imig, Beate Wuellner, Christine Wittig, Carsten Zwick, Axel Mischo, Kristin Waetzig, Bernd F.M. Romeike, Werner Lindemann, Martin Schilling, Michael Pfreundschuh, Christoph Renner Pages: 117-125

Optical diagnosis of cervical cancer by fluorescence spectroscopy technique Siddappa M. Chidananda, Kapaettu Satyamoorthy, Lavanya Rai, Attibele P. Manjunath, Vasudevan B. Kartha Pages: 139-145


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Friday, April 07, 2006

Diabetes studies conflict on power of spleen cells

Recently, a series of papers showed Reversal of Diabetes in Non-Obese Diabetic Mice without beta cell regeneration derived from spleen-cell or hematopoietic cells.

Couzin J. Immunology. Diabetes studies conflict on power of spleen cells. Science. 2006 Mar 24;311(5768):1694. No abstract available.
PMID: 16556811 [PubMed - indexed for MEDLINE]

Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science. 2006 Mar 24;311(5768):1774-5.
PMID: 16556844 [PubMed - indexed for MEDLINE]

Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science. 2006 Mar 24;311(5768):1775-8.
PMID: 16556845 [PubMed - indexed for MEDLINE]

Suri A, Calderon B, Esparza TJ, Frederick K, Bittner P, Unanue ER. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science. 2006 Mar 24;311(5768):1778-80.
PMID: 16556846 [PubMed - indexed for MEDLINE]

Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL. Islet regeneration during the reversal of autoimmune diabetes in NOD mice.Science. 2003 Nov 14;302(5648):1223-7.
PMID: 14615542 [PubMed - indexed for MEDLINE]

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Tuesday, April 04, 2006

Good new for MA residents

Massechussett state was about to become the first state that provides universal health insurance to its resident. The ones who are able to pay for private insurance will be penalized on state tax, if they do not pay for it.

For more, visit New York Times.

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