Friday, April 07, 2006

Diabetes studies conflict on power of spleen cells

Recently, a series of papers showed Reversal of Diabetes in Non-Obese Diabetic Mice without beta cell regeneration derived from spleen-cell or hematopoietic cells.

Couzin J. Immunology. Diabetes studies conflict on power of spleen cells. Science. 2006 Mar 24;311(5768):1694. No abstract available.
PMID: 16556811 [PubMed - indexed for MEDLINE]

Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science. 2006 Mar 24;311(5768):1774-5.
PMID: 16556844 [PubMed - indexed for MEDLINE]

Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science. 2006 Mar 24;311(5768):1775-8.
PMID: 16556845 [PubMed - indexed for MEDLINE]

Suri A, Calderon B, Esparza TJ, Frederick K, Bittner P, Unanue ER. Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells. Science. 2006 Mar 24;311(5768):1778-80.
PMID: 16556846 [PubMed - indexed for MEDLINE]

Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL. Islet regeneration during the reversal of autoimmune diabetes in NOD mice.Science. 2003 Nov 14;302(5648):1223-7.
PMID: 14615542 [PubMed - indexed for MEDLINE]


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